Fluorination of 2-substituted benzo[b]furans with Selectfluor™.
نویسندگان
چکیده
An efficient protocol was developed to access 3-fluoro-2-hydroxy-2-substituted benzo[b]furans with Selectfluor™ as the fluorinating reagent in MeCN and water. By utilizing SOCl2/Py as the dehydrating agent, the compounds above were readily converted to 3-fluorinated, 2-substituted benzo[b]furans in high yields.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 11 شماره
صفحات -
تاریخ انتشار 2015